Lilly Principal Research Scientist - Structure Based Drug Design - Technical in Alcobendas, Spain
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.
At Lilly, we serve an extraordinary purpose. We make a difference for people around the globe by discovering, developing and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism.
The Discovery Chemistry Research and Technologies (DCRT) organization within Lilly Research Labs is a small molecule drug discovery organization with responsibilities spanning from target identification to candidate selection for clinical studies. We are looking to grow our diverse team of scientists. The Computational Chemistry and Cheminformatics (C3) group in DCRT is seeking multiple drug hunting experts with experience applying advanced computational technologies to real-world structure-based drug design (SBDD) applications.
Design complex molecules and predict their properties using cutting-edge technologies integrating structural, chemical and biological data
Contribute to the strategy and execution of small molecule drug discovery programs, working closely with cross-functional project teams in a matrix environment
Lead by example in the application of in silico technologies to small molecule drug discovery programs
Champion and promote the use of computational chemistry and cheminformatics methods to expedite the Design-Make-Test-Analyze discovery cycle.
Innovate and implement new technologies to accelerate and improve small molecule design
Identify and assess emerging computational methodologies, including AI/ML, and contribute to the scientific development direction for the group.
Mentor scientific staff and contribute to their scientific and career development.
Ph.D. in Cheminformatics, Computational Chemistry, Computer Science, Bioinformatics or related field plus 5+ years of relevant drug hunting experience in a biotech or pharma setting
Demonstrated impactful contributions to drug design programs as exemplified by authorship on peer-reviewed publications and/or inventorship on patents/patent applications
Examples of impactful contributions to small-molecule drug discovery programs with structure-based drug design, physics-based simulation methods, or ab initio calculations
Experience working cross-functionally with colleagues in MedChem, Structural Biology, Pharmacology, ADME/Tox, and other functions
High-level proficiency in scripting or programming languages such as Python
Proficiency in programming computational workflows in Knime or equivalent
Extensive expertise with molecular design software tools
Strong oral and written communication skills, organizational and leadership capabilities.
Ability to work in a Linux/Unix enterprise environment
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