Lilly Postdoctoral Research Scientist-Neuroscience Delivery-FDE in Cambridge, Massachusetts
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.
Lilly is passionate about the discovery, development and commercialization of potential new medicines that will impact and improve the lives of patients. Our New Therapeutic Modalities team is an innovation-focused group striving to identify, develop and apply the most ground breaking technologies to deliver maximum benefit to our patients. Our agile and diverse team strives to operate as an autonomous ‘biotech-like’ company within the walls of Lilly.
We are looking for creative and energetic problem solvers to contribute to a multidisciplinary team at the front edge of innovation. We are building state-of-the art expertise in major oligonucleotide-based modalities and delivery approaches, with an emphasis on innovative strategies with potential for breakthrough efficacy and translation to patients.
In our fast-paced, interdisciplinary team we utilize novel RNA/oligonucleotide based therapeutic modalities to enhance the Lilly portfolio. We work closely with the Neuroscience Next Generation Therapeutics group to support the development of medicines for chronic pain and neurodegenerative disorders.
The successful applicant will utilize their knowledge and technical expertise to drive development of novel approaches for maximizing nucleic acid modalities to treat neurological diseases. Do you have an aptitude for innovative approaches focused on identifying impactful therapies for the patient? We want you on our team! Some responsibilities in this role are:
Develop formulation / administration techniques to support effective delivery of nucleic acids to the CNS
Design and execute animal studies to discriminate the pharmacokinetic and pharmacodynamic characteristics of delivery approaches
Optimize and drive innovation in animal administration techniques
Collaborate cross-departmentally within Lilly in work that requires expertise and input across the organization
Present scientific strategy, experimental data, and project updates across the organization
Develop, validate, and implement characterization techniques / analytical assays as needed to drive project
PhD in Biomedical Engineering, Neuroscience, Biology, Chemical Engineering, Pharmaceutical Sciences, or related fields
Excellent communication skills and the ability to work in a highly dynamic and collaborative environment
Experience in nucleic acid structure, function, formulation, and delivery
Experience in in vivo studies, particularly as related to neuroscience
Experience in pharmacokinetic / pharmacodynamic modelling
Familiarity with characterization techniques for nucleic acids / nucleic acid formulations
Familiarity with analytical assays to quantify and evaluate efficacy of nucleic acids
This posting is not permanent. It is for a fixed duration of two years with potential to extend annually for up to 4 years.
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At Lilly we strive to ensure our employees are part of a team that cares about them and our shared purpose of making life better for those around the world. How do we do this? We continue to look for ways to include, innovate, accelerate and deliver while maintaining integrity, excellence and respect for people. We hope that you seek to join us on our journey as we create medicine and deliver improved outcomes for patients across the globe!