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Lilly Postdoctoral Research Scientist-RNA Nanomedicine-FDE in Cambridge, Massachusetts

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Lilly is passionate about the discovery, development and commercialization of potential new medicines that will impact and improve the lives of patients. Our New Therapeutic Modalities (NTM) team is an innovation-focused group working to identify, develop and apply ground breaking technologies to deliver maximum benefit to our patients. Our agile and diverse team strives to operate as an autonomous ‘biotech-like’ company within the walls of Lilly.

We are looking for a creative and collaborative scientist with expertise in the conception, formulation, and investigation of emerging nucleic acid delivery approaches. The ideal candidate will have a strong understanding of current state-of-the-art delivery strategies and will actively seek out the expertise of scientific leaders across and beyond Lilly. The candidate will draw on that knowledge and their scientific background to contribute to a multidisciplinary team at the front edge of innovation.

In this role, you will be exposed to the full breadth of preclinical and clinical drug discovery at Lilly and will provide opportunities to contribute to the development of breakthrough medicines. Therefore, you must demonstrate a history of strong technical depth, scientific leadership, and scientific communication. We embrace a highly collaborative, team-based approach to scientific work.

Do you have an interest in innovative approaches focused on identifying impactful therapies for the patient? If you have a strong understanding of emerging nucleic acid delivery technologies, we want you on our team!

Key responsibilities

  • Drive innovation in nucleic acid drug delivery platforms, driving optimization through formulation science, rational design, in silico modeling, and design of experiments.

  • Drive rapid and conclusive in vitro and in vivo evaluations of diverse drug delivery formulations and approaches.

  • Serve as a member of an integrated and collaborative team responsible for discovery of nucleic acid-based therapies.

  • Communicate to management team to enable / accelerate business decisions.

  • Engage in a highly collaborative work environment across and beyond NTM and Lilly, including external academic researchers and pre-competitive collaborations.

  • Publish and present original research externally, author internal technical documents.

Basic Qualifications:

PhD in Biomedical Engineering, Chemical Engineering, Pharmaceutical Sciences, or related field.

Additional Skills/Preferences:

  • Expertise in nanomedicines and delivery approaches i.e. CNS delivery.

  • Experience in coarse-grain and/or flow modeling, scale-up of nanformulations

  • Proven experience in areas relevant to nucleic acid drug delivery: e.g. tissue-specific delivery, cellular uptake mechanisms, encapsulation and self-assembly processes.

  • Prior experience with nucleic acid purification and characterization

  • Prior experience designing and performing in vivo studies

  • Ability to take initiative and work without oversight

  • Excellent verbal communication and documentation skills

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

As a condition of employment with Eli Lilly and Company and its subsidiaries in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide proof of vaccination satisfactory to the company. If you would like to request an accommodation for medical or religious reasons, you may do so at workplace_adjustment@lilly.com.

At Lilly we strive to ensure our employees are part of a team that cares about them and our shared purpose of making life better for those around the world. How do we do this? We continue to look for ways to include, innovate, accelerate and deliver while maintaining integrity, excellence and respect for people.​ We hope that you seek to join us on our journey as we create medicine and deliver improved outcomes for patients across the globe!

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