Lilly Scientist-RNA Formulation in Cambridge, Massachusetts
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.
The Lilly New Therapeutic Modalities (NTM) team is looking for hardworking and motivated scientists to join our Innovation Hub in Cambridge, MA. We pursue ground breaking research in a highly interdisciplinary environment to enable the next generation of nucleic acid delivery technologies. These technologies will expand the impact of our existing pipeline in small-interfering RNAs (siRNA) and our emerging pipeline in additional nucleic acid modalities. We work with colleagues across NTM and therapeutic areas to discover therapies that could change the lives of our patients, their families and the world.
Are you able to execute well in a laboratory, troubleshoot, optimize assays and strive to produce clear results? Lilly is looking for someone like you to join our team! We value our employees, communities and the patients we serve and want you to be part of our efforts. Apply today!
The successful candidate will have a strong research background in nucleic acid formulation / characterization and / or wet lab biology techniques. Additionally, they should be detailed and analytically-minded while embracing and supporting an open, communicative, and collaborative work environment. The scientist will collaborate with a multidisciplinary team to perform experiments to aid characterization and development of nucleic acid delivery strategies for the next generation of genetic therapies.
Formulation and characterization of novel nucleic acid delivery constructs; Relevant techniques include preparation of nanoparticles (e.g., lipid nanoparticles), agarose / PAGE gel electrophoresis, DLS, SEC, HPLC
In vitro evaluation of these constructs including techniques such as cell culture, qPCR, Western blot, etc.
Optimization of protocols for characterization and evaluation of constructs
Visualization, summation, and presentation of results to team members
B.S. or M.S. in Biomedical Engineering, Biology, Chemical Engineering, Pharmaceutical Sciences, or related fields
Excellent communication skills and the ability to work in a highly dynamic and collaborative environment
Experience in nucleic acid structure, function, formulation, and delivery
Experience with cell culture and molecular biology techniques
Familiarity with characterization techniques for nucleic acids / nucleic acid formulations
Familiarity with analytical assays to quantify and evaluate efficacy of nucleic acids
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At Lilly we strive to ensure our employees are part of a team that cares about them and our shared purpose of making life better for those around the world. How do we do this? We continue to look for ways to include, innovate, accelerate and deliver while maintaining integrity, excellence and respect for people. We hope that you seek to join us on our journey as we create medicine and deliver improved outcomes for patients across the globe!