Lilly Scientist-Formulations in Greenfield, Indiana
This Scientist/ Sr. Scientist position directly supports the Pharmaceutical, Vaccine, Science and Technology (PVS&T) organizations. The primary responsibility of this role is to characterize product quality attributes and develop robust formulations and formulation processes needed to advance Elanco’s early and late phase Biomolecules portfolio. The formulations scientist will provide hands-on, day-to-day technical support of all formulation lab activities covering the broad scope of Elanco’s large molecule portfolio (nutritionals, vaccine and biotherapeutics). Responsibilities will include but are not limited to experimental design and analysis, technical program leadership, collaboration with internal and external partners and technology transfer. Beyond the lab responsibilities, this role deliverables will also include authoring and executing SOPs, batch records and technical reports. The formulation scientist position is a high visibility position that can serve as a contributor and/or lead scientist on the various product and species teams for R&D and manufacturing. This position will be responsible for implementing and optimizing a panel of assays to evaluate protein solubility, stability, aggregation, charge, and homogeneity. This position is laboratory-based and will require routine interaction with scientists across multiple discovery and core research laboratories at Elanco. Beyond the technical requirements, this position will require organizational management and excellent communication skills. The incumbent scientist will be expected to support multiple projects at any given time. The ability to independently conceptualize and execute experiments, coupled with a “can do” attitude, is essential.
Functions, Duties, Task:
Perform analyses using a variety of modalities including but not limited to capillary electrophoresis, HPLC/UPLC (hydrophobic interaction, analytical size exclusion, reverse phase, affinity), dynamic light scattering, differential scanning calorimetry, solubility determination, microflow imaging, and melting curve analyses.
Screen buffer compositions for compatibility with protein solubility and formulation needs.
Conduct routine analysis of large molecule candidates using existing SOPs and regulatory guidelines as well as performing equipment troubleshooting when needed
Develop and validate various analytical methods for product release while keeping meticulous records
Facilitate technology transfer with internal and external partners
Author technical reports, SOP’s, batch records and tech transfer documents
Keep abreast of scientific literature in the field and implement novel developability screening protocols and instrumentation.
Provide expertise in evaluation of new platform technologies.
Exceptional problem solving and decision-making skills. Highly focused and detail oriented
Effective oral and written communications skills.
Must be able to work productively in an interdisciplinary team environment
Two years of experience working on R&D projects in the human or animal health industries
Proven project leadership skills
Knowledge and experience in using Design-Of-Experiments and statistical software
Knowledge and experience in high throughput sample design and analysis
Experience in writing analytical protocols and development reports
Experience with downstream processing and/or formulations of vaccines and/or therapeutic proteins a plus
Elanco is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
BS degree in a relevant scientific discipline (Chemistry, Biology, Biochemistry, Engineering or related field)
New Grads welcome
Qualified candidates must be legally authorized to be employed in the United States. Elanco does not anticipate providing sponsorship for employment visa status (e.g., H-1B or TN status) for this employment position.
Elanco is a global research-based company that develops and delivers product and services to enhance animal health and production. We value innovation, both in scientific research and daily operations, and strive to cultivate a collaborative work environment for more than 7,000 employees worldwide. Founded in 1954, Elanco is a division of Lilly. Our worldwide headquarters and research facilities are in Greenfield, Indiana.
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