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Lilly Advisor - Drug Product Developability in Indianapolis, Indiana

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Organization Overview:

At Lilly, we serve an extraordinary purpose. We make a difference for people around the globe by discovering, developing and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism.

Position Brand Description:

The Synthetic Molecule Design and Development (SMDD) department within the Lilly Research Labs is an integrated synthetic molecule drug development organization which spans drug discovery and development phases from early discovery to submission and post-approval. Our scientists and engineers develop innovative technical and business solutions across a portfolio of projects using their deep technical expertise to accelerate testing of the clinical hypothesis and overall drug development. Through recognizing the value of a hardworking, diverse, and inclusive workforce, SMDD delivers on these responsibilities and helps bring the next generation of life changing medicines to patients.

Our team is looking for highly motivated, creative, and upbeat candidates who will work on the integration of early drug discovery, preclinical, and clinical activities with a focus on drug product design and development.


Candidates must possess a strong background in fundamental pharmaceutical sciences (including formulation development, biopharmaceutics, and solid state) and be able to integrate this understanding with knowledge of disease state, therapeutic area, patient preferences and molecular properties to develop drug products that enable project development. Specific responsibilities for this role include:

  • Producing sophisticated, enabling formulations (i.e. spray-dried dispersions, cyclodextrins, colloids, in-situ salts, high concentration solutions) at small, benchtop scale.

  • Characterizing solubility, dissolution, and physical and chemical stability of drug candidates and formulations using various analytical techniques, including chromatography, microscopy, thermal analysis, and X-ray diffraction.

  • Modeling absorption of drug candidates from molecular properties and preclinical data.

  • Designing and developing preclinical and clinical formulations that enable drug delivery of a broad range of potential drug molecules

  • Collaborating with discovery scientists (including chemistry, ADME, toxicology, and pharmacology) to characterize the physicochemical properties of synthesized molecules and influence selection of clinical drug candidates.

  • Partnering with solid state and biopharmaceutical modeling scientists to identify an appropriate solid form and drug delivery technology that provides vital pharmacokinetic profile and enables preclinical and clinical studies.

  • Identifying and mitigating technical risks for the performance and production of clinical drug products.

  • Demonstrating exceptional teamwork and learning agility to solve complicated technical problems and to identify and implement novel formulations, drug delivery technologies, and clinical study designs that improve benefit to our patients and value to Lilly.

  • Embracing diverse thoughts, backgrounds, and experiences to deliver innovative pharmaceutics solutions that will allow the company to realize its vision of Next Generation Research.

  • Engaging and influencing the external scientific community to foster collaborations for innovation and to advance Lilly’s internal portfolio.

Basic Requirements:

  • B.S. (with at least 10 years of drug delivery experience), M.S. (with at least 6 years of drug delivery experience), or Ph.D. in Pharmaceutics or other related field

Additional Skills/Preferences:

  • Deep understanding of biopharmaceutics and pharmacokinetic principles, formulation development and pharmaceutical material sciences, and drug product factors impacting in vivo performance and manufacture

  • Basic understanding of regulatory aspects pertaining to development and clinical testing of drug products

  • General understanding of solid-state forms, screening and instrumentation used in characterization of pharmaceutical solids

  • Experience supervising or guiding the work of other scientists

  • Strong teamwork, communication and writing skills

Additional Information:

  • Possible exposure to chemicals, allergens, and loud noises. .

  • Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities participate in the workforce and ensure equal opportunity to compete for jobs. If you are an individual with a disability and require a reasonable accommodation to participate in the application process, please email Lilly Recruiting Compliance. Please note, this email address is intended for use only to request a disability accommodation, please email Lilly Recruiting Compliance for further assistance. Inquiries which are not requests for accommodations may not receive a response.

  • Occasional travel

Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

As a condition of employment with Eli Lilly and Company and its subsidiaries in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide proof of vaccination satisfactory to the company. If you would like to request an accommodation for medical or religious reasons, you may do so at