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Lilly Associate Scientist (Analytical Development – Biophysical Characterization) in Indianapolis, Indiana

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Organization Overview:

The pharmaceutical industry is a complex, constantly evolving environment, and we are looking for highly motivated, capable, and adaptable team members to help us continue bringing innovation to patients.

Bioproduct Research and Development (BRD) is an innovation-focused organization within Lilly Research Laboratories. BRD is involved in key activities for the development of parenteral biologics drug substance and drug products including synthetic organic drug products from pre-clinical phases through commercialization. You will be part of dynamic department made up of a diverse team of molecular and cell biologists, purification and process engineers, pharmaceutical scientists, analytical chemists, and engineers. We strive to identify, develop, and apply groundbreaking technologies to deliver maximum benefit to our patients. BRD delivers on these responsibilities by recognizing diverse talent and backgrounds are vital to bring the next generation of novel medicines to patients. BRD Analytical is a flexible, cross-functionally integrated, and capabilities driven team within BRD committed to providing state of the art measurement sciences to guide product and process understanding leading to optimized control strategies. Our mission is to elucidate understanding at molecular level, define critical quality attributes, integration of CMC knowledge, establish new platforms and technologies, and achieve regulatory acceptance to commercialize life changing medicines.


We are seeking an outstanding candidate to join the biophysical characterization group within BRD Analytical. You will contribute to one or more project teams. Key job responsibilities include performing biophysical characterization of active pharmaceutical ingredients and drug product dosage forms, elucidating their properties and interactions with other components in support of the process or product development, and generating data to support regulatory filings and transfer of methods and techniques to manufacturing sites and partner testing laboratories.

Responsibilities include:

  • Using appropriate biophysical tools and techniques.

  • Development of characterization methods, set-up, operation, and troubleshooting of equipment.

  • Collaborate with other scientists and teams.

  • Identify internal and external customer requirements, develop solutions to meet customer needs. Efficiently and effectively handle project results to provide support for multiple projects at multiple phases. May serve as the project lead for one or multiple projects within the area depending on experience level.

  • Maintain awareness of biophysical and analytical sciences and pharmaceutical industry trends. Openly share technical knowledge and key findings.

  • Demonstrate good documentation skills for raw data recording and data reporting. Be proficient with interpretation of the results. Exercise good scientific judgment and call out technical issues in an appropriate manner.

  • Author technical reports and regulatory documents.

  • Support organizational initiatives.

  • Work effectively with external partners on outsourcing efforts and research collaborations.

  • Ensure the work is aligned with all relevant Quality, regulatory, and HSE requirements.

Basic Qualifications:

  • BS degree and 3-5 years pharmaceutical industry experience, or MS degree in Chemistry / Biophysical Chemistry / Biophysics / Chemical Engineering or similar technical or scientific fields.

Additional Skills/Preferences:

  • Demonstrated hands-on proficiency in a research laboratory setting.

  • Good documentation skills and ability to author and/or review standards, GMP guidelines, SOPs, templates, protocols, and other documentation.

  • Excellent general technology skills (such as MS Office) and the ability to compile, summarize and present information to diverse groups.

  • Ability to follow tasks based assignments with attention to details, perform sample forecast, retrieve, and compile data from appropriate databases. Demonstrated self-management, task planning and organization, problem solving skills.

  • Effective oral and written communication skills.

  • Ability to adapt and learn quickly. Ability to troubleshoot problems and identify solutions.

  • Thorough understanding of protein, peptide, and nucleic acid chemistry, structure, and function.

  • Knowledge of biophysical techniques used to assess higher order structure of proteins, peptides, and oligonucleotides such as UV/Vis, CD, FTIR, fluorescence; thermal stability techniques such as DSC, ITC, UV/Vis and CD temperature ramp; separation techniques such as SEC, SV-AUC, AFFF; light scattering techniques such as DLS, SLS/MALS; particulate counting and characterization is a plus.

  • Demonstrated ability to work productively in a multidisciplinary team environment. Customer-focused demeanor.

Additional Information:

  • Possible exposure to chemicals, allergens, and loud noises

  • Location: Indianapolis, IN

  • Travel: 0 to 15%

Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

At Lilly we strive to ensure our employees are part of a team that cares about them and our shared purpose of making life better for those around the world. How do we do this? We continue to look for ways to include, innovate, accelerate and deliver while maintaining integrity, excellence and respect for people.​ We hope that you seek to join us on our journey as we create medicine and deliver improved outcomes for patients across the globe!