Lilly Associate Scientist - In Vivo Pharmacology in Indianapolis, Indiana
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.
At Lilly, we serve an extraordinary purpose. We make a difference for people around the globe by discovering, developing and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism
We are seeking a highly motivated laboratory-based scientist with a strong background in behavioural pharmacology to join the Lilly Pain Drug Discovery team. The ideal candidate will be a critical thinker, experienced in animal handling, dosing, animal surgery and demonstrated expertise in behavioural pharmacology. The candidate will be an integral part of multiple teams focused on developing novel medicines across broad pain disorders. Therefore, the ability to interact collaboratively with scientists with diverse expertise is a prerequisite for this role.
The primary responsibilities of the candidate will be to support multiple in vivo animal studies in the Pain Drug Discovery group.
Demonstrates exceptional ability to work with fellow lab/team members in order to schedule, coordinate, and execute high-quality in vivo studies
Displays problem-solving skills and the knowledge of inter- and intra-departmental roles and responsibilities for coordination of work activities
Communicates with senior pharmacologist and other lab/team members regarding study activity, scheduling, and/or findings
Displays innovative skills to accommodate various study designs
Design and conduct of rodent (mouse and rat) in vivo pharmacology studies
Planning the study in collaboration with the senior pharmacologist
Randomizing, blinding, formulating, dosing of test compounds to study animals (PO, SC, IM, IV, IP)
Collecting behavioral data of various modalities (manual observation and automated)
Accurately documenting clinical observations, dosing times, dosing volume, bleeding times, body weights, food consumption and unscheduled events
Collecting fluid and tissue samples (plasma, CSF, other tissues) at study termination and for larger studies conducting by other scientists
Processing, labeling, and delivering samples for analysis internally and externally
Analyzing data, graphically representing data and statistically analyzing data
Recording data in notebook, presenting in laboratory/project meetings
Demonstrates aseptic procedures
Prepares animals for surgery, monitors animals for pain during and post-surgery and administers proper anesthetic
Conducts various surgical models, including nerve ligation
Demonstrates command of rodent dissection and prosection
Coordinates all preparations for the conduct of necropsies and demonstrates proficient dissection techniques
Delivers high-quality tissue samples
- Ensures full compliance with all Lilly regulations, including understanding and following all Animal Care and Use protocols
- High school diploma or equivalent with relevant animal handling/dosing experience.
5+ years industry experience
Bachelor’s or Master's Degree in Biology or related field.
Demonstrated proficiency in dosing and handling mice and rats.
Skilled in sample collection (plasma, CSF, tissue dissection) and sample preparation.
Ability to work collaboratively in a team environment
Flexibility and adaptability to a changing work environment with changing priorities.
Strong organizational, multi-tasking, and time-management skills.
Skilled in small animal surgical techniques.
Experience conducting pain-related behavioral pharmacology studies in mice and/or rats.
Excellent written and oral communication skills, ability to document experiments clearly and according to Good Research Practice principles.
Interest / aptitude in Machine Learning
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