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Lilly Associate Scientist Neuroscience Research in Indianapolis, Indiana

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Organization Overview

At Lilly, we serve an extraordinary purpose. We make a difference for people around the globe by discovering, developing and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism.

Lilly Neuroscience is seeking a dedicated scientist to join Neurobiologicals Group to facilitate its mission of discovering novel medicines for the treatment of Alzheimer’s disease, Parkinson’s disease, and other related neurodegenerative conditions. You will contribute to research focused on developing therapeutics in close collaboration with other Neurodegeneration laboratories as well as Lilly Genetic Medicines, Chemistry and Biotherapeutic engineering divisions. A substantial focus of the role will be the supporting development and implementation of in vitro/in vivo blood brain barrier (BBB) receptor-mediated transport models for siRNA based therapeutics. Do you possess hands-on laboratory and in-vivo experience, a keen interest to understand the molecular and cellular mechanisms that underlie non-invasive drug delivery to the CNS, and have an outstanding attention to scientific detail? This role would be a great fit.

Key Objectives:

  • Contribute to development of mammalian cell culture assays with cell lines and primary neurons.

  • Design and develop assays.

  • Analyze changes in gene and protein expression from cell cultures and tissues by RT-qPCR, ELISA and fluorescence imaging.

  • Perform high throughput imaging and data analysis of cell cultures and brain tissue sections.

  • Record, analyze and communicate scientific data with high attention to detail.

  • Ability to thrive in a high productivity environment by continually implementing new ways to improve throughput.

Basic Qualifications

  • Bachelor's Degree and/or Master's Degree in Biochemistry, Molecular and cellular biology, Neuroscience, or a related field

Additional Skills/Preferences

  • Robust assay development experience.

  • Attention to detail to develop consistent and reproducible mammalian cell culture assays using cell lines and primary neurons

  • Hands on experience with RT-qPCR or ELISA assays and/or experience with assay automation using a liquid handler.

  • Experience in utilizing high content imaging equipment (e.g. Cytation 5, Opera, Operetta) and developing protocols and analyzing images to generate study reports and figures.

  • Problem-solving skills and creativity with a willingness to search and review the scientific literature independently.

  • Have accurate and timely record keeping and strong data analysis and organizational skills.

  • Able to clearly communicate data and work independently in order design and troubleshoot experiments.

  • Experience with in vitro assay development and drug discovery in industry.

Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( LillyRecruitingCompliance@lists.lilly.com ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.

As a condition of employment with Eli Lilly and Company and its subsidiaries in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide proof of vaccination satisfactory to the company (subject to applicable law).

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