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Lilly Biologist-In Vivo Discovery Research in Indianapolis, Indiana

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

The Lilly Diabetes and Complications Research organization has created a research team focused on discovery and preclinical development of new therapeutics in the areas of Diabetes, Obesity and Complications. We are looking for an experienced in vivo pharmacologist with an excitement for and track record of accomplishment in drug discovery and development. The candidate will have experience in the development, validation, and implementation of in vivo assays with which to develop new therapeutics. Do you have skills to coordinate rodent studies in a team environment to support both small and large molecule projects and new gene editing initiatives? We invite you to join our diverse and dynamic team!

Primary responsibilities will include performing proof-of-concept studies, in vivo assay development and optimization, and execution of studies to support target validation and lead optimization. We collaborate with the Chemistry, Biotherapeutics, and Genetic Medicines groups in a team-oriented environment and support other groups in the Diabetes and Complications Therapeutic Area as needed.

Other responsibilities in this role:

  • Perform acute and chronic in vivo studies including mouse and rat handling, blood, and tissue collection, measurement of blood-based biomarkers, body weight and food intake as well as test article formulation and administration by oral gavage, subcutaneous, intravenous, retro-orbital and intramuscular injection.

  • Assessment of clinical chemistries, body composition analysis, respiratory quotient and other parameters of metabolism

  • Perform small animal surgical procedures including, but not limited to, rodent catheter and mini pump implantation

  • Conduct experiments using radioisotopes, chemicals, and biological hazards

  • Accurate record keeping, independent data analysis, and written and oral reporting of data. Perform work in full compliance with Lilly Research Policies, and complete all required training activities in the timeframe specified

Basic Requirements

  • BS or MS in biology or a closely related field

  • Laboratory and in vivo research experience highly preferred

Additional Skills/Preferences

  • Familiarity with setting up and running biochemical assays, evaluating ex vivo primary tissue assays, conducting cell culture, and conducting protein analysis and transcription profiling

  • Ability to work in flexible, team-oriented environment

  • Experience in diabetes and/or metabolic diseases is preferred

  • In vivo experience with in vivo gene editing, telemetry, body composition analysis, and survival surgery

  • Strong relationship-building and interaction skills with peers and management

  • Oral and written communication skills in English.

Additional Information:

Flexible scheduling is a requirement. The position is full-time (40 hrs/wk), but not all regularly scheduled work hours will occur Mon-Fri from 8 AM-4:45 PM. There is a requirement to work after-hours or on weekends on occasion.

The position level will be commensurate with the candidate’s experience. The position is governed by regulations including OSHA, AAALAC, OLAW and NRC — compliance to all applicable regulations is required. Travel requirement 0-10%.

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As a condition of employment with Eli Lilly and Company and its subsidiaries in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide proof of vaccination satisfactory to the company (subject to applicable law).