Lilly Biologist - Translational Immunology in Indianapolis, Indiana
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.
We are the Discovery and Translational Immunology team, and we are looking for a hardworking associate scientist with experience in laboratory based immunological methods to join our team. Our mission is to identify mechanism-relevant pharmacodynamic biomarkers for assets in Lilly’s immunology pipeline and develop drug tailoring hypotheses in various autoimmune diseases that can be assessed in clinical trials. The identification of translational biomarker strategies will use samples from both preclinical models and human-derived sources.
The position offers an outstanding opportunity to impact the tailoring of Lilly’s autoimmune therapies to the most suitable patients based on novel biomarkers. The successful candidate needs to have hands-on expertise in bioanalytical techniques (multiplex cytokine assays, assay development, etc.), human cell manipulation and culture, molecular biology techniques, and multi-parameter flow cytometry. If you are an independent and an enthusiastic scientist with the ability to work well with cross-functional colleagues supporting the Lilly autoimmune portfolio.
Do you have demonstrated research experience and solid understanding of the immune system? This may be the perfect role. Consider bringing your talents to an organization dedicated to its employees and the patients we care about! We look forward to having you join the Lilly family!
Experience with human blood mononuclear cells
Experience with immunological assays (e.g., multiplex bead-based ELISAs, ultra-sensitive ELISA systems (e.g., MSD, Quanterix)), multi-parameter flow cytometry, in vitro functional assays with primary human cells, isolation of rare human primary cell population out of blood, biochemical techniques (PCR, western blotting, protein phosphorylation), etc.
Strong background in applying and developing bioanalytical techniques (assay development and qualification) for application to human clinical trial sample analysis in-house or transfer to CROs.
Work with project teams and cross-functional partners to identify and validate human translatable biomarkers, especially related to pharmacodynamic response and generation of tailoring hypothesis to be tested in clinical trials in autoimmune diseases
Record, analyze and communicate scientific data to supervisor/manager and project teams with clear interpretation of results and proposed next steps
Proficiency with Microsoft Office, GraphPad Prism, etc necessary for data analysis and organization of large datasets
Maintain high laboratory standards with regard to quality, safety and general laboratory housekeeping
We are looking for a scientist who can summarize and visualize their data. are you scientifically curious and able to troubleshoot experiments? Join us today!
Bachelors of Science with at least 1 year of relevant research experience or training or Masters in Immunology, Cell Biology or related scientific field
Excellent collaboration skills and team spirit
Relationship owner of TPO interactions
Understand principles of genetics and how they apply to autoimmune diseases
Experience in a pharmaceutical and/or biotechnology environment
Ability to contribute to project teams, with clearly defined critical paths, achievements and timelines
Excellent written and oral communication skills with high proficiency in written and spoken English
Ability to critically interpret data
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As a condition of employment with Eli Lilly and Company and its subsidiaries in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide proof of vaccination satisfactory to the company (subject to applicable law).