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Lilly Director / Sr. Director - Biotechnology Discovery Research Lead Optimization in Indianapolis, Indiana

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

The Biotechnology Discovery Research Lead Optimization (BioTDR-LO) group at Lilly’s Technology Center in Indianapolis advances medicines that address significant unmet needs by integrating biology with innovative scientific capabilities in biomolecule design. We collaborate with colleagues across Lilly, including scientists in biomolecule discovery, engineering, and computational sciences, Therapeutic Area biology, ADME, Toxicology, PK/PD, Statistics, Clinical Development, and more. Our team is looking for a motivated technical leader with deep expertise in biomolecule design/optimization and broad knowledge of drug development to join us and make a difference for the patients and communities we serve! The successful candidate will lead efforts to design and optimize protein therapeutics balancing desired biological function with manufacturability in a dynamic research environment.

Responsibilities:

  • Provide exceptional scientific and operational leadership to overcome barriers and drive projects and platforms forward with speed and quality.

  • Partner closely with colleagues across Lilly, including other groups in BioTDR, Medicines Innovation Hub, ADME/Toxicology/PKPD, and therapeutic areas. Ensure teams work together effectively across boundaries. Represent BioTDR on select cross-functional initiatives.

  • Supervise and mentor senior scientists and research associates and ensure rigorous performance management practices. Coach, mentor, and develop talent more broadly.

  • Innovate to improve core technologies and build next-generation capabilities

  • Actively engage with the broader scientific community by reading scientific and trade literature, attending/presenting at meetings and conferences, and authoring original research publications. Identify, champion, and deliver opportunities to create value from the external environment.

Basic Qualifications:

  • Ph.D. in biochemistry, biophysics, (structural) biology or related field

  • 7+ years biologics research and development experience in pharmaceutical and/or biotechnology companies

Additional Skills/Preferences:

  • 10+ years of relevant experience with 7+ years of supervisory experience

  • Experience with design and characterization of protein-small molecule conjugates

  • Demonstrated ability to grasp and lead in a breadth of scientific areas spanning molecule biology, purification, biophysical and bioanalytical characterization of biomolecules

  • Excellent communication, interpersonal, and leadership skills are essential

  • Proven ability to navigate complex business and technical issues and ensure timely delivery

  • Proven track record of developing innovative solutions and driving continuous improvement

Additional Information

  • We will consider candidates at higher level than Director

  • Location: Indianapolis, IN

  • Travel: Less than 10%

Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( LillyRecruitingCompliance@lists.lilly.com ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Our employee resource groups (ERGs) offer strong support networks for their members and help our company develop talented individuals for future leadership roles. Our current groups include: Africa, Middle East, Central Asia Network, African American Network, Chinese Culture Network, Early Career Professionals, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinos at Lilly, PRIDE (LGBTQ + Allies), Veterans Leadership Network, Women’s Network, Working and Living with Disabilities. Learn more about all of our groups.

As a condition of employment with Eli Lilly and Company and its subsidiaries in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide proof of vaccination satisfactory to the company (subject to applicable law).

#WeAreLilly

At Lilly we strive to ensure our employees are part of a team that cares about them and our shared purpose of making life better for those around the world. How do we do this? We continue to look for ways to include, innovate, accelerate and deliver while maintaining integrity, excellence and respect for people.​ We hope that you seek to join us on our journey as we create medicine and deliver improved outcomes for patients across the globe!

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