Lilly Formulation/Delivery Scientist in Indianapolis, Indiana
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.
At Lilly, we unite caring with discovery to make life better for people around the world. Eli Lilly & Company’s Biotechnology Discovery Research organization is responsible for discovering and optimizing novel biotherapeutic (oligonucleotides, proteins, peptides, antibodies) medicines for advancement into clinical research. Key areas of unmet medical need we focus on include diabetes, oncology, immunology, neuroscience, and others. A crucial component for success is enabling the generation of drug candidates containing biopharmaceutical properties that ensure successful manufacturing, formulation, and drug delivery.
Can you work collaboratively across diverse teams? We work cross-functionally with research and development groups. We focus on biophysical characterization and developing strategy for biotherapeutic molecules, working together to accomplish our goals. We are looking for a hardworking scientist experienced in drug delivery to join our efforts! Apply today!
The ideal candidate will:
use hands-on polymer synthesis experience for delivery of biologics/nucleic acids
employ conjugation chemistry expertise of polymer/lipid to ligands (SM, peptides, etc.)
develop, optimize, and scale analytical methods and high throughput assays aimed at identifying and prioritizing the right molecule(s) with the desired properties to enable successful pre-clinical and clinical development
manage formulation development and analytical characterization of diverse biotherapeutic molecules to enable preclinical assessment in vitro, ex vivo, and in vivo using multiple models with minimal direction
have significant hands-on experience using multiple instruments including HPLC/UPLC, SEC, UV/VIS spectrometer, fluorescence spectrometer, analytical ultracentrifuge, NMR, FT-IR, static/dynamic light scattering, electron microscopes (AFM, SEM, TEM), DSC, viscosity
design and execute experimental studies with critical attention to details; collect, interpret, summarize, and present the results in project meetings and other forums; document all outcomes in electronic notebooks following established procedures
review external literature to identify and evaluate areas of innovation to accelerate the delivery of critical breakthroughs and achieve positive impact on project outcome
B.S.or M.S. degree in chemical engineering, organic chemistry, biochemistry, chemistry, pharmaceutical sciences, with a minimum of 3 years (for MS) and 5 years (for BS) of relevant work experience
Concepts of active targeting in drug delivery
Analytical characterization, cell culture, etc.
Hands-on experience working with formulation development (particles, hydrogels, etc) and analytical characterization of biotherapeutic molecules like peptides, peptide-nucleic acid conjugates, biopolymers, sugars, and bioconjugates
Demonstrated success in working independently and as part of a large cross-functional team
Strong communication and interpersonal skills vital to establish productive collaborative relationships to deliver project results on time
Agility to learn and implement new technical skills to address research challenges or fill critical knowledge gaps
Flexibility to prioritize as project/platform objectives evolve
Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( LillyRecruitingCompliance@lists.lilly.com ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.
Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
As a condition of employment with Eli Lilly and Company in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide valid proof of vaccination to the company.
At Lilly we strive to ensure our employees are part of a team that cares about them and our shared purpose of making life better for those around the world. How do we do this? We continue to look for ways to include, innovate, accelerate and deliver while maintaining integrity, excellence and respect for people. We hope that you seek to join us on our journey as we create medicine and deliver improved outcomes for patients across the globe!