Lilly In Vivo Biologist-Neuroscience in Indianapolis, Indiana
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.
Our Neuroscience organization is doing amazing research impacting patients around the world. We have an exciting opportunity for an in vivo biologist to join our Neurodegenerative research team. You will be part of a diverse group of research scientists, clinicians, statisticians, and business professionals working with internal and external partners across multiple geographical locations. Our group seeks to identify, explore, and deliver on therapies for novel neurodegenerative disease targets, increasing mechanistic understanding across a broad range of platforms (e.g. small molecule, large molecule, and oligonucleotides). We are seeking an experienced and innovative scientist to join our interdisciplinary team to enhance our portfolio. Top candidates for this position will be able to:
Work with project team leads to design and plan in vivo experiments to support the preclinical characterization and evaluation of therapeutic molecules.
Perform rodent drug delivery including, but not limited to, oral gavage (p.o.) dosing, and subcutaneous (s.c.), intraperitoneal (i.p.), and intravenous (i.v.) injections.
Perform central nervous system (CNS) tissue dissection, trimming, and processing, and collect body fluids (e.g. blood).
Support technology and methodology development for improving the delivery of novel therapeutics to regions of interest in the rodent CNS.
Assist with drafting and refining procedures within Animal Care and Use Protocols, organizing animal study cohorts, working with colleagues to complete complex studies, and providing study and sample details to internal and external partners.
Work independently as well as within a flexible team-oriented environment.
Demonstrate excellent communication, both written and oral, and collaboration skills across functional boundaries.
Demonstrate strong operational skills including exceptional prioritization and execution of multiple tasks simultaneously.
Do you have the skills and desire to contribute to groundbreaking research? Apply today and join the Lilly Family!
BA, BS, or MS degree in Neuroscience or related fields with applicable in vivo training or experience.
Experience in developing and working with neuroscience-relevant in vivo models to support drug discovery programs.
Hands-on proficiencies in designing and completing in vivo pharmacological experiments across neuroscience indications.
Knowledge of brain and spinal cord anatomy.
Knowledge of drug delivery in key CNS regions in animal models, including experience with stereotaxic surgeries and various types of injections, including intracerebral (i.c.) and intracerebroventricular (i.c.v.).
Strong expertise in CNS tissue dissection, including spinal cord, tissue processing, and cerebrospinal (CSF) and plasma/serum fluid collection (e.g. tail clip, mandibular, and cardiac blood collections).
Support the development and implementation of behavioral studies aimed at elucidating disease progression and therapeutic pharmacodynamic effects in neurodegeneration-relevant rodent models.
Experience in developing and completing assays on collected rodent samples, such as qRT-PCR, immunoassays, and histology, to support drug discovery programs.
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As a condition of employment with Eli Lilly and Company and its subsidiaries in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide proof of vaccination satisfactory to the company (subject to applicable law).