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Lilly Operator-Purification Pilot Plant in Indianapolis, Indiana

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Organization Overview:

At Lilly, we serve an extraordinary purpose. We make a difference for people around the globe by discovering, developing and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism.

We are seeking new team members to join our Bioprocess R&D Team supporting our clinical trial pilot plant. This is a great opportunity to join a team that helps make medicines for patients everywhere.


In this role, you will deal with 4 main branches of work tasks. These include:


  • Make buffers and media from various raw materials.

  • Perform in-process tests of media and buffers

  • Fill media and buffer into process containers

Inoculation Lab

  • Develop inoculum for microbial and mammalian culture products

  • Perform bioburden testing for the bioreactors and media operations

  • Submit samples to vendor partners for further evaluation.

Cell Culture/Primary Recovery

  • Transfer inoculum from the inoculation lab to the bioreactors/fermenters

  • Monitor, feed, and harvest feed cell culture

  • Clean/Steam equipment with clean/steam-in-place cycles and in cabinet washers


  • Receive buffers from the makeup area

  • Purify harvested material with various purification techniques (chromatography, viral filtration, tangential flow filtration, etc.).

  • Fill the final active pharmaceutical ingredient (API) into storage containers

We are seeking individuals that will contribute to the overall goal of the group and display the following skills:

1- Technical Ability: You will operate and oversee process equipment and related systems in accordance with approved tickets and procedures. In addition, you must be willing to accept new assignments, projects, and challenges as assigned by supervision, be capable of troubleshooting issues as they occur, and identify trends and ways to reduce process variability.

2- Data Management/Compliance: You should exhibit a high level of attention to detail and a quality-minded approach to all record keeping. Accurate and legible records must be maintained and analyzed to provide detailed information on the status of their operations. All documentation must follow cGMP practices as defined by Corporate, Divisional, and Local procedures/tickets, policies and practices.

3- Communication Skills, Oral and Written: This position may require interaction with Quality Team members, Bioproduct Research and Development scientists, Analytical Services, Operations, Technical Services Representatives, Engineering, and Maintenance personnel. Strong communication and understanding of technical information, with regards to the area, are important.

4- Safety and Environmental Awareness : to You will adhere and promote all safety and environmental guidelines.

Minimum Qualification Requirements:

  • High School Diploma or GED

  • Qualified candidates must be legally authorized to be employed in the United States. Lilly does not anticipate providing sponsorship for employment visa status (e.g., H-1B or TN status) for this employment position.

  • Completion of Post Offer Exam or Completion of Work Simulation if applicable.

Additional Preferences:

  • Exhibit strong communication and teamwork skills

  • Exhibit dedication and commitment to delivering on tasks

  • Ability to interact and build effective relationships with a wide range of groups.

  • Manufacturing operations experience preferred

  • Experience with computer software such as Excel and Word

  • General interpersonal and communication skills; coaching, feedback, training, and fostering an environment for learning and open/honest communication.

  • Basic analytical and problem-solving skills.

Additional Information:

  • Shifts can vary for each area. Flexibility is required to accommodate different production shifts, possibly including night work.

Personal Considerations:

  • Work environment includes administrative and production settings.

  • Safety glasses, safety shoes, and appropriate gowning, such as Tyvek suits, are required in production areas.

Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

As a condition of employment with Eli Lilly and Company in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide valid proof of vaccination to the company.

At Lilly we strive to ensure our employees are part of a team that cares about them and our shared purpose of making life better for those around the world. How do we do this? We continue to look for ways to include, innovate, accelerate and deliver while maintaining integrity, excellence and respect for people.​ We hope that you seek to join us on our journey as we create medicine and deliver improved outcomes for patients across the globe!