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Lilly Plant Process Engineer in Indianapolis, Indiana

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Organization Overview:

For 140 years, Lilly has manufactured medicines that improve people’s lives around the world. We produce our medicines using some of the most sophisticated manufacturing technologies and rigorous quality standards. Lilly Manufacturing strives for excellence in its process, standards, procedures and behaviors to develop medicines with safety first and quality always.

Plant Engineering in Indianapolis Parenteral Manufacturing is responsible for maintaining the site’s facility infrastructure including buildings, HVAC, GMP utilities, steam, water, sewer and other utility systems to a state of compliance. It must assure that facilities and related infrastructure are fit for use when needed, maintenance and reliability techniques are efficient and effective, and appropriate corrective and improvement actions are taken when necessary. Plant Engineering is also responsible for the efficient and effective management of local capital for their assets and oversight of engineering/maintenance contract resources.


The Plant Engineer is responsible for establishing and maintaining the reliable operation and qualified state of the equipment and business processes in the areas they support. This includes HVAC, Utilities, and ancillary systems associated within their facilities. The Plant Engineer ensures that equipment is in-control, compliant, and capable of meeting customer needs, while also driving associated continuous improvement initiatives.

  • Understand HVAC applications in aseptic manufacturing, Utilities and GMP Utilities (WFI, Clean Steam, PCA, etc.).

  • An understanding of mechanical equipment used in a manufacturing environment (Pumps, motors, etc.).

  • Ensure a safe working environment by following safety rules and helping improve the safety culture.

  • Develop scope for capital projects targeted at both short and longer term needs.

  • Act as user representative for capital projects or delivery agent for local projects.

  • Monitors/trends control systems.

  • SME on flow charts and process parameters.

  • Perform process monitoring - routine alarm reviews / reports / C4I.

  • Responsible for troubleshooting problems.

  • Engaged on communication to customers for system issues.

  • Technical leader and mentor for Sr. Specialists.

  • Responsible for the evaluation of all activities that have the potential to impact the qualified state for their system(s).

  • Responsible for all CAPA and observation/deviation investigations and originations (e.g. root cause analysis).

  • Change Control owner for applicable systems.

  • Participates in Process Team.

  • HVAC and Utility SME for audits.

  • Responsible for periodic reviews of systems and procedures.

  • Lead or participate in IQ/OQ/PQ activities (including commissioning activities).

  • Lead or participate in capital projects for applicable HVAC and utility systems in area(s) of responsibility.

  • Responsible for equipment reliability issues & maintenance strategy with the objective of improvement.

  • Identify and drive improvement opportunities (procedural changes, upgrades, projects, etc.) associated with equipment & processes within the area.

  • Participate/Provide oversight in ensuring scheduled shutdowns are planned and executed effectively.

Basic Requirements:

  • Bachelors Degree in Engineering

Additional Preferences:

  • Strong problem solving skills.

  • Technical understanding of HVAC and Utilities (including rotating equipment).

  • Good interpersonal and communications skills.

  • Ability to work effectively in a cross-functional environment.

  • Ability to communicate effectively with all levels of the organization.

  • Strong computer skills in a variety of software packages (SAP, Excel, JMP, etc.).

  • Responsible for maintaining a safe work environment, working safely and accountable for supporting all HSE Corporate and Site Goals.

  • Previous experience within the Pharmaceutical Industry.

  • Ability to apply statistical thinking concepts to the analysis of manufacturing.

  • Good Business Acumen.

Additional Information:

  • Standard business hours (days, M-F) with after-hour support and shutdown support as needed.

  • Minimal travel required.

  • Applicant will work in various areas within Indianapolis Parenteral where allergens may be present. Mobility requirements and exposure to allergens should be considered when applying for this position.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

As a condition of employment with Eli Lilly and Company and its subsidiaries in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide proof of vaccination satisfactory to the company. If you would like to request an accommodation for medical or religious reasons, you may do so at

At Lilly we strive to ensure our employees are part of a team that cares about them and our shared purpose of making life better for those around the world. How do we do this? We continue to look for ways to include, innovate, accelerate and deliver while maintaining integrity, excellence and respect for people.​ We hope that you seek to join us on our journey as we create medicine and deliver improved outcomes for patients across the globe!