Lilly Post-Doctoral Research Scientist-Statistical Genetics - FDE in Indianapolis, Indiana
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.
At Lilly, we have a history of addressing the needs of individuals living with Diabetes by providing breakthrough therapies that result in significant improvements in patients’ lives. We continue to build on this history through research and development efforts that seek next generation therapies. We have one of the largest pipelines in Diabetes in the industry and are committed to continuing to build our leadership in Diabetes and its complications through innovation in drug discovery and development. Lilly strives to employ innovative post-doctoral researchers who are dedicated to the science as well as our community and the world in which we live.
The Diabetes and Complications Therapeutic Area (DCTA) has an exciting opportunity for a post-doctoral fellow who can apply statistical knowledge and methodologies for better interpretation of human genetic data. Have you imagined using your data and statistical analysis skills in pursuit of drug development? Learn, contribute and apply state-of-the-art analytical methods to explore how genetics play in shared connections across type 2 diabetes (T2D) and its related complications. We'll strive to develop a refined genetic understanding for disease etiology/mechanism and maximize the value of human genetics in diabetes drug target discovery and validation. The successful candidate will utilize datasets that are publicly available along with Lilly-internal clinical trial genetics, and other proprietary deep-phenotyped datasets.
As part of the Bioinformatics & Genetics group at DCTA you will work in a highly collaborative, multidisciplinary environment of scientific excellence. This role offers regular interactions with Lilly internal scientists who have equipped labs, infrastructure and deep expertise. We encourage diverse perspectives and contributions that will help advance Lilly diabetes drug discovery. Consider joining Lilly's efforts today!
Key Responsibilities include:
Contribute to the developing science of diabetes drug target identification and genetic validation
Apply statistical methods that integrates genetic association strength with functional annotations and explore underlying biology/potential causal T2D mechanism(s).
Analyze public and Lilly internal datasets to understand how T2D and related complications share common genetic risk profiles
Identify and explore how genetic factors contribute to disease susceptibility through relevant endophenotypes; discover dysregulated pathways for diabetes and related traits
Test causal relationships between biological processes (genetics and biomarkers) and clinical outcomes using mendelian randomization framework
Perform genetic analyses, interpretation and communication of large-scale human genetic and phenotypic data
Ability to work with others in a collegiate and collaborative environment
Present data at scientific conferences and publish in peer-reviewed journals
PhD degree in statistical genetics, human/population genetics, genetic epidemiology, biostatistics or other related analytical field
Additional Preferred Skills
Proficiency in at least one programming language (ideally Python or R), experience in statistical methods and data modeling in high-dimensional human genetics/genomics environment.
Experience and knowledge of conducting large-scale GWAS/meta-analyses, phenome-wide (PheWAS), whole-exome sequencing, mendelian randomization, genomic colocalization etc.
An attention to detail and a drive for excellence
Strong verbal and written communication skills with peer-reviewed publication record
Working experience in diabetes and metabolic diseases is not vital, but a plus
This position is not permanent. It is for a fixed duration of two years with potential to extend annually for up to 4 years.
About Eli Lilly’s Postdoctoral Scientist Program
When it comes to research and development, our goal is to discover and deliver innovative medicines that make life better for people around the world. It’s challenging, expensive and often filled with failure. But even when we fail, we advance medical science and understanding by learning more about diseases, biology and chemistry – ultimately bringing new solutions one step closer to reality.
Over the course of our history, we have shed light on some of the toughest health care problems known to man – diabetes, heart disease, infectious diseases, neuroscience disorders, cancer and more. We could not pursue this without our research and development team.
Postdoctoral scientists help us continue this pursuit. During your experience you will get:
Top industry research experience
Mentoring by some of Lilly’s top scientists
Training and coaching opportunities to further your development
Collaboration and networking across other postdoctoral scientists and researchers
Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( LillyRecruitingCompliance@lists.lilly.com ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.
Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
At Lilly we strive to ensure our employees are part of a team that cares about them and our shared purpose of making life better for those around the world. How do we do this? We continue to look for ways to include, innovate, accelerate and deliver while maintaining integrity, excellence and respect for people. We hope that you seek to join us on our journey as we create medicine and deliver improved outcomes for patients across the globe!