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Lilly Post-Doctoral Scientist (FDE) – Synthetic Molecule Design & Development - Absorption, Distribution, Metabolism & Excretion in Indianapolis, Indiana

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Organization Overview:

At Lilly, we serve an outstanding purpose. We make a difference for people around the globe by discovering, developing and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism.


We are seeking an ambitious post-doctoral scientist with strong research and interpersonal skills to contribute to high visibility research projects. Your work will contribute to the development of tools and techniques to assess the impact of supersaturation and precipitation on oral dosage form absorption. This research will not only improve the general understanding of oral absorption but also enable the development of drug products with outstanding performance characteristics. In this role, you will:

  • Design and conduct experiments to measure in vivo relevant supersaturation and precipitation.

  • Apply innovative thermodynamic and kinetic models to describe supersaturation and precipitation phenomena

  • Define methodologies such that they will readily interface with current in silico oral absorption models.

  • Investigate sensitivity of the techniques to important experimental parameters (fluid composition, residence time, mixing dynamics, degree of supersaturation, scale). Refine and validate the techniques based on findings.

  • Focus on defining clear scientific hypothesis, goals and fit-for-purpose experimental plans and timelines in support of advancing the Lilly portfolio.

  • Keep abreast of relevant scientific literature/new technologies/capabilities.

  • Effectively integrate cross-functional information and apply technical knowledge to data-driven decisions.

  • Identify areas of key need across drug development and champion creative solutions to address those needs. Maintain external awareness and learning to benefit the organization.

  • Present findings at conferences and publish in high quality peer-reviewed journals.

Basic Qualifications

  • Ph. D. in Pharmaceutical Sciences, Chemistry, Chemical Engineering, or related field

Additional Skills/Preferences

If you are described with these skills, you could be a great fit for the role:

  • Self-directed and highly motivated individual who wants to learn new techniques while continually pursuing research and publication goals.

  • Excellent communicator (oral and written) with presentation experience, along with a strong publication record.

  • Experience in oral absorption and bio pharmaceutics.

  • Knowledge and experience with oral dosage form performance, supersaturation and precipitation phenomena.

  • Understanding of analytical measurements and techniques, including UV/Vis and/or HPLC

  • Experience with modeling methodologies used to describe oral absorption and related physical processes.

  • Proficiency in computer programming languages and computational techniques

  • Excellent problem solving and decision-making skills.

  • Proficient in data analysis and reporting.

  • Demonstration of scientific leadership skills.

  • Able to work efficiently in an interdisciplinary team environment.

Additional Information

  • This position is not permanent. It is for a fixed duration of two years with potential to extend to 3 years and for maximum of up to 4 years. You will have opportunities to apply for full time positions after your duration is complete.

About Eli Lilly’s Postdoctoral Scientist Program

When it comes to research and development, our goal is to discover and deliver innovative medicines that make life better for people around the world. It’s complicated, expensive and often filled with failure. But even when we fail, we advance medical science and understanding by learning more about diseases, biology and chemistry – ultimately bringing new solutions one step closer to reality.

Over the course of our history, we have shed light on some of the toughest health care problems known to man – diabetes, heart disease, infectious diseases, neuroscience disorders, cancer and more. We could not pursue this without our research and development team.

Postdoctoral scientists help us continue this pursuit. During your experience you will get:

  • Top industry research experience

  • Mentoring by some of Lilly’s top scientists

  • Laboratory and classroom training and education to further your development

  • Collaboration and networking across dozens of postdoctoral scientists and other researchers

Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

As a condition of employment with Eli Lilly and Company and its subsidiaries in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide proof of vaccination satisfactory to the company (subject to applicable law).