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Lilly Principal Research Scientist-SMDD Automation and Data Informatics in Indianapolis, Indiana

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Company Overview

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our over 34,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We are looking for people who are determined to make life better for people around the world.

Department Description:

Synthetic Molecule Design and Development (SMDD) is an innovation-focused organization in Eli Lilly and Company. Our dynamic group is made up of chemists, chemical engineers, analytical chemists, and pharmaceutical scientists. We strive to identify, develop and apply groundbreaking technologies to deliver maximum benefit to our patients. Within SMDD, chemistry and engineering are essential to establishing a robust and sustainable supply chain for small molecules as well as other synthetic molecules such as peptides, oligonucleotides and antibody-drug conjugates. We seek to use new technologies for key problems, and we endeavor to improve the way we develop and manufacture therapeutic molecules.

Are you a creative and innovative scientist? Do you have a unique technical skills and are you driven to improve those around you? Are you interested in using laboratory automation to help drive the commercialization of synthetic clinical therapeutics? Do you have a desire and vision to integrate and apply data sets to predict solutions and solve ambitious problems? If yes, this can be the right position for you to make an impact and improve the future of drug manufacturing. You will have the opportunity to collaborate across diverse scientific areas including chemical synthesis development, chemical engineering, analytical chemistry, as well as computational chemistry and emerging machine learning fields.

Responsibilities:

Top candidates for this position will be expected to:

  • Provide strategic oversight for HTE, automation and data informatics at Lilly

  • Provide critical evaluation of technology footprint to enable and deliver evaluation, development and execution of new scientific processes

  • Adaptation of manual processes to automated platforms, mapping existing process, implementing new technology and resolving areas of improvement.

  • Work with engineering and IT teams to enable integration of systems and deliver high quality hardware and software solutions for research.

  • Develop and create data platforms and experimental templates which align with HTE capabilities creating data streams for accelerating design and development of innovative synthetic technologies.

  • Command of scientific informatics and data visualization tools (e.g. StarDrop, TIBCO Spotfire, KNIME) to undertake computationally enabled multi-parameter optimization approaches.

  • Partner with the IDS organization to develop a sustainable data ecosystem which integrate within Lilly’s existing information infrastructures.

  • Aid in building and implementing an enterprise-wide strategy for integrating the fields of data sciences and automation to create innovative solutions and approaches to addressing key issues in development of pharmaceutical therapies.

  • Integrate in silico and computational chemistry and related chemoinformatic solutions into business workflows for synthetic molecule commercialization work.

  • Partner with similar SMDD capabilities in partner areas such as automated crystallization and salt screening to identify alignment and areas for collaboration especially data platforms.

  • Robust track record of scientific contributions including peer reviewed publications, patents and presentations and maintain presence scientific meetings, consortiums, etc.

  • Effectively communicate project(s) status, issues, and strategies to various management and collaborator groups.

  • Embrace and celebrate diversity by using a relevant but unique background and set of experiences to provide new and refreshing ideas and thoughts to deliver innovative solutions for a multidisciplinary team. Strong communication (oral, written), organizational, and leadership skills are expected.

  • Contribute to a healthy, supportive work culture and maintain a highly organized laboratory area with a strong focus on all aspects of chemical and occupational safety.

Basic Qualifications:

  • PhD in Chemistry, Engineering, Informatics, Data Sciences and/or Computational Chemistry or related field

  • At least 3 years of data science experience

Additional Skills/Preferences:

  • Demonstrated leadership capabilities especially in a team environment

  • Good interpersonal skills and a persistent tendency for collaboration; excellent ability to communicate and understand customer expectations

  • Demonstrated self-initiative and appropriate risk-taking

  • Sustained technical proficiency and integration of complex scientific concepts to create technical agendas that supply business value

  • Knowledge and experience with management of technical projects

  • Ability to prioritize multiple activities and manage ambiguity

  • An active scientific curiosity and interest for complementary subject areas within the pharmaceutical industry

  • Demonstrated success in persuasion and influence in a scientific setting

  • Proficiency in use of Excel, Spotfire and data analysis software and data visualization tools

  • Expertise with big data technologies (Azure/AWS) is preferred

Additional Information:

  • Potential exposure to chemicals, allergens and loud noises

  • Travel: 0 to 10%

  • Position Local: Indianapolis, IN; Lilly Technology Center-North (LTC-N)

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

As a condition of employment with Eli Lilly and Company and its subsidiaries in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide proof of vaccination satisfactory to the company. If you would like to request an accommodation for medical or religious reasons, you may do so at workplace_adjustment@lilly.com.

At Lilly we strive to ensure our employees are part of a team that cares about them and our shared purpose of making life better for those around the world. How do we do this? We continue to look for ways to include, innovate, accelerate and deliver while maintaining integrity, excellence and respect for people.​ We hope that you seek to join us on our journey as we create medicine and deliver improved outcomes for patients across the globe!

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