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Lilly Research Fellow, Genetic Therapies in Indianapolis, Indiana

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

At Lilly, we serve an extraordinary purpose. For more than 140 years, we have worked tirelessly to discover medicines that make life better. These discoveries start in Lilly Research Laboratories, where our scientists work to create new medicines that will help solve our world’s greatest health challenges.


The Lilly New Therapeutic Modalities Team is seeking an experienced and inspired scientific leader to join our fast-paced, interdisciplinary team as we leverage novel RNA/oligonucleotide based therapeutic modalities to enhance and advance the Lilly portfolio. The successful applicant will utilize their knowledge and technical expertise to complement and enable core capabilities of next generation oligonucleotides and RNA modalities, driving the discovery and development of RNA-based clinical candidates.

Key facets of the role are setting strategy and scientific direction for next generation of genetic therapies at Lilly, assembling and progressing an innovative preclinical portfolio with focus on scientific rigor, portfolio effectiveness, and building and maintaining state of the art expertise in oligonucleotide-based modalities, with an emphasis on innovative approaches with potential for breakthrough efficacy.

The New Therapeutic Modalities team strives to operate as a small, agile and autonomous ‘biotech-like’ company within the walls of Lilly. In the RNA Team, both basic and applied sciences are essential. We are looking for creative and energetic problem solvers to work in a multidisciplinary team across the breadth of the Lilly organization to achieve the company’s objectives for future pipeline growth and value for the patient.

Platform Leadership

  • Provide leadership on approaches to improve mechanistic understanding of RNA/oligonucleotide-based therapeutics

  • Lead efforts in the design and discovery of innovative oligonucleotide chemistries and conjugations to small molecules, peptides or monoclonal antibodies that will enable tissue selective delivery

  • Provide scientific direction and leadership on novel delivery system(s) and vehicles for RNA therapeutics

  • Leverages diverse cross-functional and external network to enhance innovation and break-through thinking in research and development of oligonucleotide therapeutics

  • Embrace diversity of thought, background and experience to deliver innovative solutions in the face of ambiguity

People Leadership

  • Work with cross-functional project teams providing scientific updates, and project management support required to achieve pre-clinical and clinical development goals and timelines.

  • Maintain a high scientific profile for the group by encouraging participation in scientific exchange, publications and presentations.

  • Manage, coach and develop direct reports and team members

  • Provide leadership to solve remaining research and development challenges in oligonucleotide space by delivering innovative solutions that expedite drug discovery and bring value for the patient

  • Identify, sponsor and accelerate development of talent across the enterprise

Basic Qualifications

  • PhD in Chemistry, Biochemistry or relevant scientific discipline with a minimum of 15-years experience in the pharmaceutical or related industry in the area of oligonucleotide-based chemistry and therapeutics

Additional Information

  • Travel: 0 to 30%

  • Position: Boston or Indianapolis, IN; Lilly Corporate Center (LCC)

Additional Skills/Preferences

  • Proven experience in design and discovery of RNA based therapeutics.

  • Demonstrated knowledge of Pharmaceutical Discovery, Development and Intellectual Property Processes.

  • Experience in leading groups of researchers including PhD level scientists.

  • Clear understanding of regulatory environments, pharmaceutical standards of care in target markets, critical relationships, and emerging technologies to provide Lilly with competitive access to opportunities of strategic interest.

  • Experience working in a matrixed environment as well as leading and using the matrix. Strong relational skills, demonstrated ability for efficient collaboration, prioritization and establishing effective work environments

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

As a condition of employment with Eli Lilly and Company and its subsidiaries in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide proof of vaccination satisfactory to the company. If you would like to request an accommodation for medical or religious reasons, you may do so at

At Lilly we strive to ensure our employees are part of a team that cares about them and our shared purpose of making life better for those around the world. How do we do this? We continue to look for ways to include, innovate, accelerate and deliver while maintaining integrity, excellence and respect for people.​ We hope that you seek to join us on our journey as we create medicine and deliver improved outcomes for patients across the globe!