Lilly Jobs

Job Information

Lilly Research Scientist - Biophysical Characterization in Indianapolis, Indiana

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

The Biotechnology Discovery Research (BioTDR) organization within Lilly Research Laboratories spans target identification to clinical candidate selection. The Lead Optimization Core group within BioTDR is seeking a scientist who is experienced in biophysical characterization to join our diverse, interdisciplinary team. We use our expertise in expression, purification, formulation, and characterization to support the discovery and optimization of a wide array of therapeutic modalities including proteins, peptides, fusions, and conjugates.

Are you a self-starter and eager to drive innovation in a fast-paced, collaborative environment? Our dedication to employees, patients and communities is unmatched, and we want you to be a part of our team! Let's do this together!


  • Develop and execute biophysical characterization strategies to build fundamental understanding and support the progression of biotherapeutic molecules into development

  • Build productive relationships within BioTDR and with partner functions and other collaborators, identifying and implementing creative solutions to drive value for the business

  • Share and acquire knowledge and insights through active participation in technical forums

  • Mentor and develop associate scientists and effectively manage relationships with vendors

  • Maintain strong engagement with the external environment through the academic literature, collaborations, involvement in technical meetings/consortia, and other professional networking

Basic Requirements:

Ph.D. in biophysics, biochemistry, chemical engineering, pharmaceutical science, or related field

Additional Skills/Preferences:

  • Experience with the application of a diverse set of biophysical techniques (e.g. calorimetry, spectroscopy, scattering, analytical ultracentrifugation) for the characterization of proteins/peptides

  • Proven track record of effective collaboration and scientific excellence as evidenced by a strong publication record

  • Strong verbal and written communication skills

  • Excellent time management and organizational skills with the ability to adapt to changing priorities and timelines

  • Experience with computational modeling (in particular, coarse-grained molecular dynamics) including experience with related structure modeling software (e.g. MOE, Rosetta)

  • Experience with biopharmaceutically-relevant systems (e.g. monoclonal antibodies, therapeutic proteins, antibody-drug conjugates)

  • Experience with handling external collaborations (academic/industry/government)

  • Experience with scripting or programming languages (e.g. R, Python, JSON)

  • Experience with statistics and statistical software (e.g. JMP), data science, data visualization

Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

At Lilly we strive to ensure our employees are part of a team that cares about them and our shared purpose of making life better for those around the world. How do we do this? We continue to look for ways to include, innovate, accelerate and deliver while maintaining integrity, excellence and respect for people.​ We hope that you seek to join us on our journey as we create medicine and deliver improved outcomes for patients across the globe!