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Lilly Research Scientist - SMDD in Indianapolis, Indiana

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.


The Synthetic Molecule Design and Development (SMDD) department within - Lilly Research Labs is an integrated synthetic molecule drug development organization which spans drug discovery and development phases from early discovery to submission and post-approval. Our scientists and engineers develop innovative technical and business solutions across a portfolio of projects using their deep technical expertise to accelerate testing of the clinical hypothesis and overall drug development. Through recognizing the value of a hardworking, diverse, and inclusive workforce, SMDD delivers on these responsibilities and helps bring the next generation of life changing medicines to patients.

Our team is looking for highly motivated, creative, and energetic candidates who will provide leadership in biopharmaceutics modeling and oral drug product performance.


The successful candidate will be:

  • Involved in the integration of early clinical and commercialization activities, including clinical study design, drug product design, formulation development and global regulatory submission support.

  • Support the design of new dosage forms and drug delivery technologies using pharmaceutical sciences knowledge, including formulation, biopharmaceutics, product performance, pharmacokinetics, and patient centered aspects.

  • Assess and predict the oral performance of drug molecules and formulations in pre-clinical species and humans.

  • Partner with and influence groups at the discovery, development, and clinical interface to solve complex technical problems and to identify and implement novel formulations and clinical study designs that maximize benefit to our patients and value to Lilly.

  • Influence and engage the external scientific community to foster collaborations to advance Lilly’s portfolio.

Minimum Qualifications

  • Ph.D. in Pharmaceutical Sciences and/or Chemical Engineering

Additional Preferences

  • Self-directed and highly motivated individual who wants to learn new techniques while continually pursuing research and publication goals.

  • Excellent communicator (oral and written) with presentation experience, along with a strong publication record.

  • Demonstrated proficiency in oral biopharmaceutics and biopharmaceutics modeling

  • Ability to develop custom models describing physical and biological processes and code these models in suitable programming languages

  • Proficiency with advanced chemical engineering principles

  • Experience with experimental techniques to evaluate drug product performance, especially for oral drug products

  • Theoretical and model-based descriptions of physical and biological processes related to biopharmaceutics and absorption

  • Formulation development and physical pharmacy of small molecules

  • Excellent problem solving and decision-making skills.

  • Proficient in data analysis and reporting.

  • Demonstration of scientific leadership skills.

  • Must be able to work productively in an interdisciplinary team environment.

Additional Information

  • Travel: 0-10%

  • Location: Indianapolis, IN

Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

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As a condition of employment with Eli Lilly and Company and its subsidiaries in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide proof of vaccination satisfactory to the company (subject to applicable law).