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Lilly Research Scientist in Indianapolis, Indiana

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.


Synthetic Molecule Design and Development (SMDD) has an exciting opportunity for a scientist to join our process development organization. You will be part of a diverse team of analytical chemists, engineers and formulators delivering product and process understanding across a broad range of pharmaceutical manufacturing platforms. In addition, you will be responsible for carrying out basic and applied research as an individual contributor in the development and implementation of advanced process analytical technology (PAT) and modeling/optimization tools focused on real-time process monitoring and control applied to continuous and/or batch drug product manufacturing processes. Top candidates for this position will be encouraged to:

  • Enable the design, development, and implementation of analytical methodologies for real-time characterization and monitoring of drug product processes and platforms.

  • Identify, develop and implement new insights.

  • Apply creative solutions to address instrument design, process integration, and data handling challenges.

  • Show strength in optical spectroscopy. Apply chemometric and first principles modeling techniques to support process development teams and, as appropriate, real-time release testing strategies.

The ideal candidate will have experience using multiple spectroscopic based analytical techniques (IR, NIR, Raman, UV) and their application to drug product development and manufacturing. The candidate must demonstrate computer proficiency with the ability to navigate multiple instrument control software and data analysis environments, capably integrate data and implement innovative data analysis workflows, have strong technical problem-solving ability, and have an internal motivation to work independently and achieve efficient, high quality results in a fast-paced environment.

Position Responsibilities:

  • Engage with scientists across Eli Lilly’s Development and Manufacturing and Quality organizations to develop a deep understanding of new initiatives and improve existing scientific processes.

  • Identify ground-breaking PAT technologies and industrial trends in analytical chemistry, chemical engineering, and continuous manufacturing.

  • Identify and utilize new scientific concepts, strong problem-solving skills, and be self-motivated to achieve quality results in a fast-paced environment.

Basic Qualifications:

  • PhD in Analytical Chemistry, Pharmaceutical Sciences, or Chemical Engineering with 0-7 years of experience.

Additional Skills/Preferences:

  • Experience with Spectroscopy-based process monitoring tools (such as NIR and Raman, etc.) including method development, validation, and data interpretation applying chemometrics, multivariate modeling, and other data manipulation tools.

  • Extensive technical knowledge of analytical instrument hardware and control software from different vendors.

  • Instrument engineering experience including design, development, or modification of analytical platforms.

  • Experience with continuous and/or batch drug product manufacturing processes.

  • General knowledge of process monitoring and control with system automation/integration.

  • Knowledge and understanding of regulatory and quality implications of a real-time monitoring in a regulated environment.

  • Demonstrated ability to rapidly learn and apply technical knowledge to meet changing project needs.

  • Flexibility to adjust priorities over time to meet organizational and scientific goals.

  • Demonstrated leadership capabilities, especially in a team environment.

  • Ability to balance multiple activities, prioritize and handle ambiguity.

Additional Information:

  • Potential exposure to chemicals, allergens, and loud noises.

  • Travel 0-10%

Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

As a condition of employment with Eli Lilly and Company in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide valid proof of vaccination to the company.

At Lilly we strive to ensure our employees are part of a team that cares about them and our shared purpose of making life better for those around the world. How do we do this? We continue to look for ways to include, innovate, accelerate and deliver while maintaining integrity, excellence and respect for people.​ We hope that you seek to join us on our journey as we create medicine and deliver improved outcomes for patients across the globe!