Lilly Jobs

Job Information

Loxo@Lilly Consultant, Scientist, Molecular Characterization, Discovery Technologies in New York, New York

Loxo@Lilly conducts discovery research, clinical development and regulatory affairs for oncology, with the goal of creating a pipeline of therapies that have the potential to make a meaningful difference for patients. Loxo@Lilly was created in December 2019, combining the Lilly Research Laboratories oncology organization and Loxo Oncology, which was acquired by Lilly in early 2019. The unit has team members in Louisville, CO, Indianapolis, IN, New York City, NY, South San Francisco, CA, San Diego, CA, Stamford, CT, and Madrid, Spain.

The Consultant Scientist in the Molecular Characterization Group, within Discovery Technologies, will be joining a dynamic group focused on executing experiments on the cutting edge of pharmaceutical sciences. This scientist will work closely with Project Teams and Discovery Informatics under the guidance of the Platform Development Scientist in Molecular Characterization to expand applications of current next generation sequencing (NGS) related platforms, as well as to develop other novel molecular platforms and applications. The successful candidate is expected to have demonstrated expertise in a variety of molecular techniques profiling DNA, RNA, and proteins. The Contract Scientist will also help design studies, execute analyses, and interpret data to support the various research programs for identified targets. The scientist will utilize innovative, high throughput, high content molecular platforms to answer genomic, transcriptomic, and proteomic questions posed by project teams across the Loxo portfolio. The Contract Scientist will also be responsible for inspecting, calibrating, cleaning the instruments within the facility at Loxo. Finally, this role will be responsible for operationalizing new techniques in collaboration with the Molecular Characterization Team. In this role, the incumbent will also be encouraged to develop their own ideas and contribute these to the broader group. They are expected to be a dynamic and motivated scientist who can drive their own experiments and research activities, while collaborating extensively with the entire organization to execute on various research programs.

Roles and Responsibilities of the Position:

  • Interact and collaborate with various Discovery functional teams to design and execute studies supporting all projects across the oncology portfolio

  • Work collaboratively with the clinical biomarker team to perform and support retrospective and exploratory efforts for clinical programs

  • Provide quality data and analyses from a variety of high throughput, high content genomic, transcriptomic, and proteomic platforms

  • Develop and implement sequencing applications related to cell free, single cell and FFPE sequencing

  • Support existing and novel targeted panel development for NGS

  • Responsible for establishing and updating lab SOPs and training lab scientists as needed

  • Develop and implement novel molecular platforms and applications

  • Work with the entire molecular characterization team to ensure all instrumentation is properly maintained and calibrated

  • Provide scientific expertise on practical implementation of molecular platforms and applications across the entire Loxo organization

  • Proper documentation and archiving of data and analyses.

  • Work interactively with project teams and discovery informatics to interpret data and prepare formal study reports

Additional roles and responsibilities:

  • Communicate results via written and oral presentations as needed

  • Discuss results with technical as well as non-technical personnel

  • Extensive cross functional communication and collaboration with internal and external parties

  • Interrogate experimental conduct of third parties/vendors

Required Qualifications and Preferred Background:

  • BS in biological sciences with 5 years of experience or MSc or PhD in biological sciences with 2-3 years of experience

  • Broad experience with multiple nucleic acid and protein expression platforms, including assay design and development

  • Experienced with high content, high throughput laboratory workflows with emphasis on quality and efficiency

  • Demonstrated experience in working collaboratively across various scientific disciplines to meet project goals and timelines

  • Flexibility to adjust priorities over time to meet organizational and scientific goals.

  • Ability to work independently and as an integral part of a larger collaborative team.

  • Demonstrated ability to succeed in a fast-paced environment, working on multiple projects with constantly changing priorities and deadlines

  • Excellent interpersonal, written, and verbal communication skills

  • Experience processing, analyzing, and interpreting large biological data sets

Physical Demands/ Travel: TBD <5%

The physical demands of this job are consistent with working in a lab.

The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

Work Environment:

This position’s work environment is in a lab.

*To perform this job successfully, an individual must be able to perform the role and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Loxo Oncology, Inc. is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

As a condition of employment with Eli Lilly and Company and its subsidiaries in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide proof of vaccination satisfactory to the company (subject to applicable law).

Loxo Oncology, Inc. (“Loxo”) is committed to help individuals with disabilities participate in the workforce and ensure equal opportunity to compete for jobs. If you are an individual with a disability and require a reasonable accommodation to participate in the application process for positions at Loxo, please email for further assistance. Please note, this email address is intended for use to request an accommodation as a part of the application process. Any other correspondence will not receive a response.