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Lilly Research Associate – Analytical Development, Gene Therapy in New York, United States

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

At Prevail Therapeutics, we are developing a pipeline of gene therapies to slow or stop the underlying disease process for patients with Parkinson’s disease and other neurodegenerative disorders. We are leveraging recent breakthroughs in human genetics that point to potential disease-modifying targets for neurodegenerative diseases. Our programs utilize a precision medicine approach targeting patient populations with urgent unmet needs, where there are currently no available therapies that modify the progressive course of their disorders.

Meet Your Future Team:

The Analytical Development team is a tight-knit group of energetic, smart, fun, and motivated individuals. We work closely on Prevail’s Adeno-Associated Virus (AAV)-based gene therapy programs to progress our mission of curing disease. We are a tight-knit group within Prevail, responsible for developing and running robust and innovative analytical methods to support internal and external manufacturing processes, while also staying on the cutting-edge of industry standards.

While much of the day-to-day operations require wet-lab work, our team focuses on not only building everyone’s technical expertise but also fostering an environment for career growth as scientists in the biopharmaceutical industry. As analytical development relates to quality, process development, preclinical and clinical R&D, manufacturing, and regulatory functions, there is opportunity for exposure to the whole scope of biopharmaceutical industry processes. We are seeking a motivated research associate who can take on ownership of established molecular biology assays as well as contribute to the development of new cutting-edge assays for testing AAVs.

Responsibilities:

  • Contribute to all aspects of analytical assay development, from design to qualification, for our AAV-based drugs.

  • Contribute to the development and qualification of new molecular bioassays for AAVs including titer, genomic integrity, and next-generation sequencing assays.

  • Perform testing in support of Prevail’s AAV programs using techniques such as ddPCR, agarose and capillary gel electrophoresis, and NGS.

  • Analyze, document, and report data.

  • Write technical reports and SOPs.

  • Communicate data within the group as well as across functions.

Basic Qualifications:

  • BS or MS with 2+ years of lab experience with molecular biology techniques.

Additional Skills/Preferences:

  • Prior experience with AAVs is desired but not necessary.

  • An analytical skill set which may include qPCR/ddPCR, next-generation sequencing, spectrophotometry, gel/capillary electrophoresis, SDS-PAGE/Western blot, or others.

  • Strong understanding of, and preferably experience with, qPCR or ddPCR.

  • Strong organizational and problem-solving skills and attention to detail.

  • A passion for learning, understanding, and advancing science.

  • Motivation to learn new skills both inside and outside the lab.

  • Ability to work independently and in a dynamic team environment.

  • Excellent verbal and written communication skills.

  • Previous experience in viral vector analytical assays design, data interpretation, and statistical analysis is a plus.

  • Previous experience in assay automation using TECAN Fluent and/or epMotion is a plus.

Additional Information:

  • Position Location: New York City, Prevail Therapeutics a wholly owned subsidiary of Eli Lilly

  • Lilly currently anticipates that the base salary for this position could range from between $53,500 to $132,500 and will depend, in part, on the successful candidate’s qualifications for the role, including education and experience. Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Of course, the compensation described above is subject to change and could be higher or lower than the range described above. Further, Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.

Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( LillyRecruitingCompliance@lists.lilly.com ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

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As a condition of employment with Eli Lilly and Company and its subsidiaries in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide proof of vaccination satisfactory to the company (subject to applicable law).

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