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Lilly Advisor - Mammalian Protein Expression in San Diego, California

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

Organization Overview

At Lilly, we serve an extraordinary purpose. We make a difference for people around the globe by discovering, developing and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism.

The Biotechnology Discovery Research Division at LBC-San Diego, responsible for generating, characterizing, and optimizing biotherapeutics from lead generation through lead optimization and preclinical development is hiring. We support cross-disciplinary efforts to engineer innovative biotherapeutics that treat metabolic, autoimmune, and neurologic diseases. Join our team of scientists working to improve lives of patients around the world.

This is an opportunity for an independent self-motivated researcher to join the Protein Bioscience Group in Lilly San Diego. We are seeking a cellular and protein expression scientist to express novel therapeutic proteins and antibody, and to work with cross functional teams in drug discovery to enable new technical capabilities. The successful candidate will lead the effort to design and implement optimal gene-to-protein workflows to generate novel therapeutic proteins and cell lines.


  • Protein and antibody production using mammalian expression platforms (transient and stable)

  • Optimization of expression plasmid and culture conditions to improve productivity

  • Clonal cell line generation through FACS/Flow analysis and cell banking

  • Partner with molecular engineers, and protein scientists to address specific project needs and challenges

  • Coordinate and present data to support decisions in cross-functional teams

  • Maintain a current knowledge in the field, attend meetings and conferences, and contribute to original research publications

Basic Qualifications:

  • Ph.D. in protein biochemistry, molecular biology, cell biology, structural biology, biophysics, or related field

  • 2+ years of relevant experience beyond Ph.D. education in a pharmaceutical, biotech, or research organization

Additional Skills/Preferences:

  • Comprehensive knowledge and extensive hands-on experience in recombinant protein and antibody production using mammalian expression systems

  • Strong hands-on experience in mammalian cell line generation

  • Knowledge and hands-on experiences in FACS/Flow analysis

  • Demonstrate strong problem-solving skills and an ability for creative thinking

  • Attention to detail with strong organizational skills and ability to handle multiple projects

  • Extensive knowledge in molecular biology, and gene manipulation techniques

  • Creative problem solver ready to work effectively with multi-functional colleagues across geographies in a collaborative, fast-paced environment.

  • Excellent written and verbal communication skills and ability to prioritize work and meet targeted timelines.

Additional Information:

  • Travel: 0-10%

  • Location: San Diego, CA

Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

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As a condition of employment with Eli Lilly and Company and its subsidiaries in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide proof of vaccination satisfactory to the company (subject to applicable law).