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Lilly Advisor-Protein Crystallography in San Diego, California

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

The Discovery Chemistry & Technologies organization within Lilly Research Laboratories is a diverse and dynamic group seeking a highly skilled scientist to join the structural biology team. We support drug discovery for numerous innovative projects and are looking for someone to inspire change in the drug hunting process. The primary focus will be to lead in the development and deployment of methodologies to accelerate structure-based drug design. Broad experience with proteins, along with a proven track record of structural determination is required. We are a diverse team of scientists and strive for excellence and innovative solutions to find therapies for our patients. Join our team today and make an impact!

Required Experience and Skills

  • Expert in protein crystallography including crystallization, structure determination and analysis; experience with construct design, protein expression and purification

  • Experience determining structures by cryo-EM will be a plus

  • Ability to lead several structural biology projects in parallel

  • Partner closely with biologists, biophysicists, biochemists, structural biologists, and medicinal chemists to develop integrative approaches to enable targets and address specific project needs

  • Work closely with groups within structural biology, and as a member of broader teams that may include synthetic chemists, computational chemists, biologists, enzymologists, and ADME scientists

  • Ability to generate macromolecular structures and communicate the relevant results to a diverse drug discovery team, and the capacity to contribute to small-molecule design efforts

Are you a highly motivated individual with the ability to thrive in a fast-paced, team-oriented drug-discovery setting? Apply today! The patient is waiting!

Basic Qualifications

PhD in biological sciences, biochemistry, chemistry, or related field with at least 2 years of relevant experience; or Master's/Bachelor’s degree in biological sciences, biochemistry, chemistry, or related field with at least 8 years of relevant experience

Additional Skills/Preferences

  • Experience in drug discovery, or with computational approaches to small molecule drug design, would be advantageous

  • Familiarity with biophysical or biochemical techniques that are complementary to X-ray crystallography

  • The position is based in San Diego, California, but the ability to conduct occasional travel to Indianapolis, Indiana (or other relevant sites) will be useful for coordinating with project teams and other colleagues

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As a condition of employment with Eli Lilly and Company and its subsidiaries in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide proof of vaccination satisfactory to the company (subject to applicable law).