Lilly Jobs

Job Information

Lilly Principal Research Scientist-Immunogenicity in San Diego, California

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 35,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world.

At Lilly, we serve an extraordinary purpose. For more than 140 years, we have worked diligently to discover medicines that make life better. These discoveries start in Lilly Research Laboratories, where our scientists work to create new medicines that will help solve our world’s greatest health challenges.

The immunogenicity research group at Lilly’s Biotechnology Center in San Diego seeks an experienced scientist with knowledge and research experience in immunogenicity assessment. The successful candidate will lead efforts to assist in the development of novel as well as implementation of established in-vitro platforms for determination of immunogenicity of various therapeutic modalities (antibodies, nanobodies, peptides, antibody-drug conjugates, RNA-based drugs, gene therapy). This will progress our research efforts and address potential molecule tolerability issues such as injection site reactions. Are you a highly motivated teammate, with a passion for goal-oriented scientific research, prior industry and supervisory experience with external influence in the area of immunogenicity or other relevant area and possessing a sound practical knowledge of immunology, cell biology, molecular biology and biochemistry? Join the Lilly Team today!


  • In-depth knowledge with in silico immunogenicity prediction analysis tools for biologics

  • Critically analyze, interpret and report experimental results. Draw appropriate conclusions and identify new strategies to assess and mitigate immunogenicity risk of biotherapeutics.

  • Prepare, review, and sign off on technical documents and reports.

  • Supervise and mentor Scientists and Research Associates as needed.

  • Provide guidance and recommendations to colleagues from cross-functional groups on immunogenicity risk assessment and mitigation strategies

  • Responsible for ensuring that all studies are compliant to relevant SOP guidelines and in line with regulatory agency expectations.

  • Lead laboratory activities and ensure scheduled work is executed as planned.

  • Organize and present data to support decisions in collaboration with the integrated immunogenicity research group.

  • Review the literature, attend meetings and conferences, and maintain an updated knowledge in the field.

  • Contribute to the preparation of scientific products, such as original research publications and presentations; writing of reports, protocols, brochures, for internal use and publication, as well as other regulatory documents when appropriate

Basic Qualifications:

Ph.D. degree in immunology, biochemistry or similar field with at least 5+ years of successful experience; a strong publication record in relevant area.

Additional Skills/Preferences

  • Analytical and problem-solving capabilities.

  • Ability to work both independently and in a team setting.

  • Able to prioritize work and meet target timelines.

  • Excellent written and verbal communication, work planning, data analysis and record keeping skills (with strong attention to detail).

  • Proficiency with Microsoft Office applications (Excel, Word, PowerPoint) required.

Eli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively “Lilly”) are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs. If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process. Any other correspondence will not receive a response.

Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

At Lilly we strive to ensure our employees are part of a team that cares about them and our shared purpose of making life better for those around the world. How do we do this? We continue to look for ways to include, innovate, accelerate and deliver while maintaining integrity, excellence and respect for people.​ We hope that you seek to join us on our journey as we create medicine and deliver improved outcomes for patients across the globe!