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Loxo@Lilly Lead Specialist (non-PhD), Proteomics in South San Francisco, California

About Loxo@Lilly:

Loxo@Lilly aims to create medicines that make life better for all those affected by cancer around the world. Bringing together the focus and spirit of a biotech with the scale, resources, and heritage of Lilly, our team is focused on rapidly delivering impactful new medicines for people with cancer. Our approach centers on creating oncology medicines that unequivocally show early signs of clinical activity and will matter to patients. We intend to curate a balanced pipeline of medicines, either internally or externally discovered, with the potential to treat cancer with dramatic effect. Loxo@Lilly was created in December 2019, combining the Lilly Oncology organization and Loxo Oncology, which was acquired by Lilly in early 2019. Loxo@Lilly is a global organization with team members in Louisville, Colorado; Indianapolis, Indiana; New York City, New York; San Diego, California; South San Francisco, California; Stamford, Connecticut; and Madrid, Spain.

This position is an opportunity to learn and grow within a dynamic discovery biology team dedicated to creating specific targeted therapeutics for genetically defined oncology targets. The ideal candidate is someone who enjoys technical challenges, has the protein handling and cell culture skills needed to drive basic oncology research forward, and will excel in a collaborative environment. Experience with cell culture and biochemical techniques will be critical. Direct experience with sample preparation and method development for mass spectrometry are desirable. The ideal candidate will be enthusiastic about cancer research and is not afraid to get their hands dirty by helping with core lab functions including cell culture, protein characterization, mass spectrometry, and laboratory automation. The qualified candidate will have experience with basic chemistry/biology laboratory practices and is passionate to learn additional techniques working in a growing and dynamic group focused on discovery research. The candidate will work as part of a collaborative team of scientists with expertise in protein characterization, cell culture, chemistry, biochemistry, structure, and biophysics, supporting hit-to-lead and lead-ID phases of our oncology drug programs. The candidate will have opportunities to learn cutting edge techniques and to learn and develop technical expertise in proteomics.

Required Qualifications and Preferred Background:

  • BA/BS or MS in Chemistry, Biology, Biochemistry, or related field

  • Ideal candidate will have hands-on 1+ years experience with cell culture, sample preparation, and sample handling within an industry or academic/research setting.

  • Excellent interpersonal skills with ability to communicate and interact well with colleagues, vendors, contractors, scientific advisors, and staff at all levels.

  • Highly organized with excellent analytical, documentation and multi-tasking skills.

  • Familiarity with Thermo Orbitrap and/or Bruker timsTOF Pro instrumentation is ideal.

  • Experience in cell line generation is a plus.

  • Experience with mass spectrometry/proteomics is a plus.

  • Expertise in other methods of enzymology or biophysical characterization and structural biology is a plus.

Loxo@Lilly currently anticipates that the base salary for the Expert Specialist level position could range from between $52,500 to $77,000 and will depend, in part, on the successful candidate’s qualifications for the role, including education and experience. This position will also be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Loxo provides a comprehensive benefit program to eligible employees, including vacation, medical, dental and vision benefits; participation in a 401(k) plan; life and accidental death and disability coverage; parental leave benefits and employee discounts for certain items. The compensation described above is subject to change and could be higher or lower than the range described.

Physical Demands/ Travel:

The physical demands of this job are consistent with laboratory setting.

The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.

Work Environment:

This position’s work environment is in a lab.

The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job.

*To perform this job successfully, an individual must be able to perform the role and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

Loxo@Lilly (Eli Lilly and Company) is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

As a condition of employment with Eli Lilly and Company and its subsidiaries in the United States and Puerto Rico, you must be fully COVID-19 vaccinated and provide proof of vaccination satisfactory to the company (subject to applicable law).

Loxo@Lilly (Eli Lilly and Company) is committed to help individuals with disabilities participate in the workforce and ensure equal opportunity to compete for jobs. If you are an individual with a disability and require a reasonable accommodation to participate in the application process for positions at Loxo, please email for further assistance. Please note, this email address is intended for use to request an accommodation as a part of the application process. Any other correspondence will not receive a response.